Author

Zhifang Lu

University of Nebraska–LincolnORCID 0000-0003-4446-5259Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Zhifang Lu2 papers · Ocean University of China

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Eliot B. BlattiD· 1 shared Feng CaiiD· 1 shared Imani M. WilliamsiD· 1 shared Islam AlshamlehiD· 1 shared Jing ZhangiD· 1 shared João S. PatrícioiD· 1 shared Jui‐Chung ChiangiD· 1 shared Lauren G. ZachariasiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Eliot B. BlattORCID

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1 paper

Recent·Most cited

NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT

Zheng Wu, Phong T. Nguyen, Varun Sondhi, Run-Wen Yao, Zhifang Lu, Tao Dai, Jui‐Chung Chiang, Feng Cai, Imani M. Williams, Eliot B. Blatt, Zeng‐Fu Shang, Ling Cai, Jing Zhang, Mya D. Moore, Islam Alshamleh, , Ralph J. DeBerardinis

This study identifies NUDT5 as a regulator of purine metabolism and thiopurine sensitivity by interacting with PPAT, independent of its known enzymatic activity.

Science · Nov 6, 2025Peer-reviewedBiochemistry