LIPT1 loss confers replication stress and PARP inhibitor sensitivity through PrimPol-mediated ssDNA gaps
Zeng‐Fu Shang, Jui‐Chung Chiang, Ching-Cheng Hsu…·Yuanyuan Zhang
This study shows that LIPT1 loss causes replication stress and PARP inhibitor sensitivity via PrimPol-mediated ssDNA gaps in cancer cells.