Author

Gábor Tax

University of LeicesterORCID 0000-0003-4530-0798Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Chelsea MayohiD· 2 shared Loretta M. S. LauiD· 2 shared Marie WongiD· 2 shared Mark J. CowleyiD· 2 shared Alvin KamiliiD· 1 shared Andrea LiaiD· 1 shared Andrew J. GiffordiD· 1 shared Andrew QuigleyiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Chelsea MayohORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CBL mutations in pediatric solid and CNS tumors are a marker of receptor tyrosine kinase activation and a potential therapeutic target

Lauren M. Brown, Chelsea Mayoh, Katherine A Camper, Gábor Tax, Pablo Acera Mateos, Wenyan Li, Sam El-Kamand, Patricia A. Sullivan, James Bradley, Paris I. Thompson, Jingwei Chen, Teresa Sadras, Robert Salomon, Marie Wong, Mark J. Cowley, , Paul G. Ekert

bioRxiv · Dec 5, 2025 · PreprintCancer Biology

Engineered paediatric tumours retain patient tumour genotype and phenotype for precision medicine.

MoonSun Jung, Valentina Poltavets, Joanna N. Skhinas, Gábor Tax, Alvin Kamili, Jinhan Xie, Sarah Ghamrawi, Philipp Graber, Jie Mao, Marie Wong, Lujing Cui, Kathleen Kimpton, Pooja Venkat, Chelsea Mayoh, Angela Lin, , Maria Kavallaris

This paper develops patient-derived tumour models using engineered ECM hydrogels to enable precision medicine for paediatric cancers by retaining tumour genotype and phenotype.

Molecular Systems Biology · Oct 1, 2025Peer-reviewedCancer Biology

C-terminal domain mobility underpins substrate engagement by the Chaetomium thermophilum EDEM:PDI ERAD-L checkpoint complex

Charlie J. Hitchman, Andrea Lia, Mohammed Bhogadia, Geander M. Pessoa, Gabriela N. Chirițoiu, Cristian V. A. Munteanu, Juan Ortigosa, Jorge Octavio Lannot, Simona Ghenea, Ikuo Wada, Maria De Benedictis, Gábor Tax, Yusupha Bayo, Irene Crescioli, Laura Sanna, , Pietro Roversi

The paper determines Cryo-EM structures of the EDEM:PDI complex with and without a substrate, revealing how disulfide bonds regulate conformational changes essential for substrate engagement.

bioRxiv · Jan 29, 2025 · PreprintBiochemistry