Brett William Stringer

This paper develops a system to produce high-purity circular RNAs by minimizing linear RNA byproducts through optimized circularization and transcript termination strategies.

The paper uses a zebrafish model to test the pathogenicity of SMN1 variants in SMA patients, showing that two variants were non-pathogenic and avoiding costly treatments.

This study uses superparamagnetic iron oxide nanoparticles with MRI to improve detection of glioblastoma vasculature and angiogenesis beyond conventional MRI contrast.

The paper introduces a toolkit for efficiently and scarlessly overexpressing circular RNAs by redesigning plasmid vectors to eliminate molecular scars at back-splice junctions.