Author

Christopher J. Fields

Baylor College of MedicineORCID 0000-0002-3151-5870Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Organism:Drosophila· 1

Frequent Co-Authors

Jeremy E. WilusziD· 2 shared Mingyi XieiD· 2 shared Rina FujiwaraiD· 2 shared Rolf RenneiD· 2 shared Aayushi P. Shah· 1 shared Bradley W. WrightiD· 1 shared Brett William StringeriD· 1 shared Casey M. Guardia· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMolecular Biology

Jeremy E. WiluszORCID

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4 papers

Recent·Most cited

Engineering circular RNA expression systems to minimize contaminating linear RNA byproducts

Christopher J. Fields, Rina Fujiwara, Bradley W. Wright, Brett William Stringer, Simon J. Conn, Jeremy E. Wilusz

This paper develops a system to produce high-purity circular RNAs by minimizing linear RNA byproducts through optimized circularization and transcript termination strategies.

bioRxiv · Sep 11, 2026 · PreprintMolecular Biology

IntS6 and the Integrator phosphatase module tune the efficiency of select premature transcription termination events

Rina Fujiwara, Si-Nan Zhai, Dongming Liang, Aayushi P. Shah, Matthew P. Tracey, Xu-Kai Ma, Christopher J. Fields, Maria Saraí Mendoza-Figueroa, Michele C. Meline, Deirdre C. Tatomer, Li Yang, Jeremy E. Wilusz

The paper shows that IntS6 recruits PP2A to regulate transcription termination efficiency at specific genes, highlighting the phosphatase module's selective role in Integrator complex function.

Molecular Cell · Nov 22, 2023Peer-reviewedMolecular Biology

Sequencing of Argonaute-bound miRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a

Christopher J. Fields, Li Lü, Nicholas M. Hiers, Tianqi Li, Peike Sheng, Taha I. Huda, Jixiu Shan, Lauren A. Gay, Tongjun Gu, Jiang Bian, Michael S. Kilberg, Rolf Renne, Mingyi Xie

The paper identifies miR-320a as a regulator of the unfolded protein response by analyzing TSS-miRNA targets in colorectal cancer cells using AGO-qCLASH.

PLoS Genetics · Dec 16, 2021Peer-reviewedMolecular Biology

A non-canonical microRNA derived from the snaR-A non-coding RNA targets a metastasis inhibitor

Daniel Stribling, Yi Lei, Casey M. Guardia, Lu Li, Christopher J. Fields, Paweł Nowialis, René Opavský, Rolf Renne, Mingyi Xie

The paper identifies a Drosha-independent miRNA, miR-snaR, derived from the snaR-A non-coding RNA, which promotes cancer cell migration by targeting NME1.

RNA · Apr 1, 2021Peer-reviewedMolecular Biology