Stephen Nicholas Sansom

HARP integrates PBMC data from multiple studies to create a reference atlas with consensus annotations and identifies age, sex, and disease-related cellular modules.

This paper introduces scTAPAS, a method to reconstruct donor genotypes from scRNA-seq data, enabling eQTL and HLA-TCR analysis without conventional genotyping.

The paper identifies resident memory T cells in the human uveal tract, showing their presence in both healthy and inflamed states and their potential role in uveitis.

This study shows that autophagy in adipocytes limits obesity-related fibrosis by controlling purine nucleoside metabolism and macrophage polarization.

Analysis of hand OA cartilage stratified by ALDH1A2 polymorphic variants reveals a targetable, anti-inflammatory role for retinoic acid in OA.

CGAT-core is a Python framework for building scalable, reproducible computational biology workflows, demonstrated with an RNAseq analysis pipeline.