This study examines thermoceptive behavior and structural changes in mouse models of CMT1A, HNPP, and aging to identify mechanisms of sensory dysfunction.

Journal of the Peripheral Nervous System · Mar 1, 2026Peer-reviewedNeuroscience

CDNF rescues motor neurons in three animal models of ALS by targeting ER stress

Francesca De Lorenzo, Patrick Lüningschrör, Jin Han Nam, Federica Pilotto, Emilia Galli, Päivi Lindholm, Cora R. von Collenberg, Simon Tii Mungwa, Sibylle Jablonka, Julia Kauder, Susanne Petri, Dan Lindholm, Smita Saxena, Michael Sendtner, Märt Saarma, Merja H. Voutilainen

This study shows CDNF reduces ER stress and improves motor neuron survival in multiple ALS models, independent of genetic cause.

bioRxiv · May 5, 2020 · PreprintNeuroscience

High contrast staining for serial block face scanning electron microscopy without uranyl acetate

Adolfo Odriozola, Jaime Llodrá, Julika Radecke, Céline Ruegsegger, Stefan Tschanz, Smita Saxena, Rohr Stephan, Benoît Zuber

The paper develops a staining method for SBFSEM that avoids uranyl acetate, providing high contrast and reducing specimen charging without radioactive substances.

bioRxiv · Oct 22, 2017 · PreprintCell Biology