Sarah M. Ruttenberg

This paper shows that an antibody targeting a structurally defined Aβ oligomer mimic protects human iPSC neurons from Aβ42 toxicity at low antibody-to-Aβ ratios.

This paper identifies that NSD1's catalytic activity is allosterically stimulated by its interaction with NONO, a paraspeckle protein, and shows this interaction is critical for neural differentiation and chromatin regulation.