Author

Maria Luisa Varela

University of MichiganORCID 0000-0003-4878-3211Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Maria Graciela CastroiD· 3 shared Pedro Ricardo LowensteiniD· 3 shared Abraham WeiiD· 1 shared Ali A. Dabaja· 1 shared Andrea CombaiD· 1 shared Andrew Robbins· 1 shared Anna A. SchwendemaniD· 1 shared Anna E. ArgentoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersCancer Biology

Maria Graciela CastroORCID

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3 papers

Recent·Most cited

Cancer BiologyMolecular Therapy OncologyPeer-reviewedApr 21, 2026

Reprogramming the Immune Suppressive Tumor Microenvironment in Glioma Enhances the Efficacy of Immune-Mediated Gene Therapy

Brandon L. McClellan, Jorge Armando Pena Agudelo, Anzar Mujeeb…·Maria Graciela Castro

This study shows that combining CD73 inhibition with immune-stimulatory gene therapy improves treatment efficacy for wtIDH1 gliomas.

DOI 10.1016/j.omton.2026.201215

mouseproteomics

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BiophysicsbioRxivPreprintApr 14, 2025

Three-dimensional topological defects and quasi-long-range order in biological liquid crystals

Anna E. Argento, Maria Luisa Varela, Gurveer Singh…·Pedro Ricardo Lowenstein

The paper identifies 3D topological defects and quasi-long-range order in glioma tumors, linking them to tumor aggression and cell density regulation.

8 citations

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Cancer BiologyAdvanced SciencePeer-reviewedFeb 22, 2024

Modeling Glioma Oncostreams In Vitro: Spatiotemporal Dynamics of their Formation, Stability, and Disassembly

Syed Mohd Faisal, Jarred E. Clewner, Brooklyn Stack…·Pedro Ricardo Lowenstein

This paper models glioma oncostreams in vitro, showing their formation, stability, and response to pharmacological agents, with insights into potential anti-invasion targets.

18 citations

mouseorganoid / primary culture

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