Monika S. Brill

The paper identifies mitochondrial transport of MAPT mRNA via SYNJ2a/SYNJ2BP complex and shows its role in maintaining Tau levels and axonal growth in glutamatergic neurons.

The paper uses proteomics to compare mitochondrial diversity in somatodendritic and axonal compartments across neurons, finding axonal mitochondria are 'impoverished' with reduced mtDNA expression and impaired oxidative phosphorylation.

The paper shows that polyglutamylation of microtubules regulates neuronal remodeling by marking them for severing, affecting synapse and axon pruning in both peripheral and central circuits.

This study identifies an axon-specific microtubule-associated protein signature that drives asymmetric regeneration in sensory neuron axons, using an in vitro model of DRG neurons.

The paper identifies a retrograde transit filter in distal axons mediated by optineurin that regulates mitochondrial homeostasis, independent of PINK1 and parkin.

The paper shows that choroid plexus cilia undergo axoneme resorption through microtubule destabilization, controlled by polyglutamylation and spastin, and is conserved in human samples.

This study shows CRMP2 is essential for Sema3F-dependent axon pruning and dendritic spine remodeling, linking its dysfunction to ASD-like behaviors in mice.

This study shows that forced Neurog2 expression in adult SEZ progenitors reprograms them to generate glutamatergic neurons, but not their postmitotic progeny.