Irene Carlón-Andrés

This study shows that Gag proteolysis drives HIV-1 Env conformational closure through the gp41 cytoplasmic tail, revealing a mechanism for immune evasion.

The paper uses cryo-electron tomography to study NiV fusion protein assemblies and shows nanobodies block inter-trimer interactions, inhibiting viral entry.

This study investigates how spike protein dynamics affect enveloped virus mobility using mesoscopic models and experimental validation.

This study shows that early HIV-1 maturation steps, specifically partial Gag cleavage, promote Env clustering and fusion competence by reorganizing the membrane-proximal lattice.

Alpha-BET uses AlphaFold to identify optimal sites for labeling viral glycoproteins with nanobodies, enabling high-resolution imaging of viral structures without disrupting their function.

The paper introduces two spectrally orthogonal chemogenetic tags for multicolor live cell imaging, enabling detection of early cell cycles and protein interactions.