Author

Alessia Gentili

London Centre for NanotechnologyORCID 0000-0002-5807-4518Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Organism:human· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Cecilia ZazaiD· 2 shared David J. WilliamsoniD· 2 shared Harry HolmesiD· 2 shared Irene Carlón-AndrésiD· 2 shared Joseph W. ThrushiD· 2 shared Michael H. MalimiD· 2 shared Sabrina SimoncelliiD· 2 shared Sergi Padilla‐ParraiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiophysics

Cecilia ZazaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Gag proteolysis drives HIV-1 envelope conformational closure through the gp41 cytoplasmic tail

David J. Williamson, Cecilia Zaza, Irene Carlón-Andrés, Harry Holmes, Alessia Gentili, Joseph W. Thrush, James L. Daly, Michael Keegan, Katie J. Doores, Tomas Malinauskas, Stuart J. D. Neil, Michael H. Malim, Sabrina Simoncelli, Sergi Padilla‐Parra

This study shows that Gag proteolysis drives HIV-1 Env conformational closure through the gp41 cytoplasmic tail, revealing a mechanism for immune evasion.

bioRxiv · Oct 4, 2026 · PreprintBiophysics

Alpha-BET: Functional labeling of envelope glycoproteins with single domain antibodies for in-virus single molecule imaging

David J. Williamson, Cecilia Zaza, Irene Carlón-Andrés, Alessia Gentili, Janet M. Daly, Harry Holmes, Joseph W. Thrush, Tobias Starling, Stuart J. D. Neil, Raymond J. Owens, Michael H. Malim, Christopher J. Tynan, Sabrina Simoncelli, Sergi Padilla‐Parra

Alpha-BET uses AlphaFold to identify optimal sites for labeling viral glycoproteins with nanobodies, enabling high-resolution imaging of viral structures without disrupting their function.

bioRxiv · Apr 11, 2025 · PreprintBiophysics