ImmunologyScience AdvancesPeer-reviewed
Fourth generation CAR Tregs with PDCD1-driven IL-10 have enhanced suppressive function
Dominic A. Boardman, Sonya Mangat, Jana K. Gillies…·Megan K. Levings
This study engineers CAR Tregs to secrete IL-10 via PDCD1-driven regulation, enhancing their suppressive function in vitro and in vivo.
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