Author

Franklin T. Moutos

Cytex Therapeutics (United States)ORCID 0009-0000-4237-2599Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Farshid GuilakiD· 2 shared Alison K. RossiD· 1 shared Benjamin L. Larson· 1 shared Bradley T. Estes· 1 shared Cameron J. Bloomquist· 1 shared Chia‐Lung WuiD· 1 shared Christine T. N. PhamiD· 1 shared Hyoungshin Park· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSynthetic Biology

Farshid GuilakORCID

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2 papers

Recent·Most cited

A Genome-engineered Bioartificial Implant for Autoregulated Anti-Cytokine Drug Delivery

Yun‐Rak Choi, Kelsey H. Collins, Luke E. Springer, Lara Pferdehirt, Alison K. Ross, Chia‐Lung Wu, Franklin T. Moutos, Natalia S. Harasymowicz, Jonathan M. Brunger, Christine T. N. Pham, Farshid Guilak

This paper develops a bioartificial implant using CRISPR-Cas9-engineered stem cells to deliver anti-cytokine drugs in response to inflammation, reducing arthritis severity in mice.

Science Advances · Sep 3, 2021Peer-reviewedSynthetic Biology

Cartilaginous and osteochondral tissue formation by human mesenchymal stem cells on three-dimensionally woven scaffolds

Benjamin L. Larson, Sarah N. Yu, Hyoungshin Park, Bradley T. Estes, Franklin T. Moutos, Cameron J. Bloomquist, Patrick B. Wu, Jean F. Welter, Robert Langer, Farshid Guilak, Lisa E. Freed

This study evaluates how human mesenchymal stem cells on 3D woven scaffolds form cartilage and bone tissue in vivo and in vitro, showing that pre-culturing affects tissue type and mineralization.

bioRxiv · Aug 19, 2018 · PreprintBioengineering