Author

Alison K. Ross

Washington University in St. LouisORCID 0000-0003-2563-220XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 1

Frequent Co-Authors

Farshid GuilakiD· 2 shared Lara PferdehirtiD· 2 shared Alireza SavadipouriD· 1 shared Amy L. McNultyiD· 1 shared Bo ZhangiD· 1 shared Chia‐Lung WuiD· 1 shared Christine T. N. PhamiD· 1 shared Christopher J. O’ConoriD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

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10 top collaborators · 30 mutual co-author links

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2 shared papersSynthetic Biology

Farshid GuilakORCID

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2 papers

Recent·Most cited

Synthetic BiologyScience AdvancesPeer-reviewedSep 3, 2021

A Genome-engineered Bioartificial Implant for Autoregulated Anti-Cytokine Drug Delivery

Yun‐Rak Choi, Kelsey H. Collins, Luke E. Springer…·Farshid Guilak

This paper develops a bioartificial implant using CRISPR-Cas9-engineered stem cells to deliver anti-cytokine drugs in response to inflammation, reducing arthritis severity in mice.

50 citationstop 2%

mouseexperimental assay

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Synthetic BiologyScience AdvancesPeer-reviewedJan 27, 2021

A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues

Robert J. Nims, Lara Pferdehirt, Noelani Ho…·Farshid Guilak

This paper develops a synthetic mechanogenetic gene circuit in engineered tissues that produces a therapeutic drug in response to mechanical loading.

85 citationstop 1%

experimental assaydrug response / drug discovery

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