Oliver J. Pambos

DeepTRACE is a machine learning tool that analyzes single-molecule tracks in living cells, uncovering molecular processes and relationships not present in training data.

This study uses single-molecule imaging in E. coli to show that RecB facilitates efficient DNA repair without activating the SOS response, while a modified RecB leads to less efficient repair and high SOS induction.

This study uses single-molecule tracking to reveal NusG's functional allocation, interactions, and spatial organization in E. coli, showing its roles in transcription elongation, anti-termination, and coupling with translation.