Author

Otto J. Mulleners

Amsterdam UMC Location University of AmsterdamORCID 0009-0000-6205-9591Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alexandra E. Giovou· 1 shared Arnie BoenderiD· 1 shared Bjarke Krogstrup JenseniD· 1 shared Diederik W.D. KusteriD· 1 shared Gerard J.J. BoinkiD· 1 shared Mathilde R. RivaudiD· 1 shared Mauro GiaccaiD· 1 shared Mischa KlerkiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperDevelopmental Biology

Alexandra E. Giovou

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1 paper

Recent·Most cited

Developmental BiologybioRxivPreprintApr 15, 2026

TBX5 dosage governs ventricular cardiomyocyte maturation, specialization and dedifferentiation in vivo

Alexandra E. Giovou, Otto J. Mulleners, Rocco Caliandro…·Vincent M. Christoffels

This study shows how varying TBX5 levels in cardiomyocytes affects their maturation, specialization, and dedifferentiation, revealing a non-linear relationship with cardiac function.

DOI 10.64898/2026.04.13.718086

mousebulk RNA-seq

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