Author

Alexandra E. Giovou

Amsterdam UMC Location University of Amsterdam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Mathilde R. RivaudiD· 2 shared Vincent M. ChristoffelsiD· 2 shared Arie O. VerkerkiD· 1 shared Arnie BoenderiD· 1 shared Bastiaan J. BoukensiD· 1 shared Bjarke Krogstrup JenseniD· 1 shared Diederik W.D. KusteriD· 1 shared Fernanda M. BosadaiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersDevelopmental Biology

Mathilde R. RivaudORCID

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Author profile →

2 papers

Recent·Most cited

TBX5 dosage governs ventricular cardiomyocyte maturation, specialization and dedifferentiation in vivo

Alexandra E. Giovou, Otto J. Mulleners, Rocco Caliandro, Vincent A J Warnaar, Arnie Boender, Mischa Klerk, Mathilde R. Rivaud, Diederik W.D. Kuster, Mauro Giacca, Bjarke Krogstrup Jensen, Gerard J.J. Boink, Monika M Gladka, Vincent M. Christoffels

This study shows how varying TBX5 levels in cardiomyocytes affects their maturation, specialization, and dedifferentiation, revealing a non-linear relationship with cardiac function.

bioRxiv · Apr 15, 2026 · PreprintDevelopmental Biology

An atrial fibrillation-associated regulatory region modulates cardiac Tbx5 levels and arrhythmia susceptibility

Fernanda M. Bosada, Karel van Duijvenboden, Alexandra E. Giovou, Mathilde R. Rivaud, Jae‐Sun Uhm, Arie O. Verkerk, Bastiaan J. Boukens, Vincent M. Christoffels

eLife · Jan 30, 2023Peer-reviewedMolecular Biology