James Philpott

This study investigates the role of the femaleless gene in Anopheles gambiae gametogenesis and its impact on CRISPR-Cas9 gene drive efficacy, showing that disrupting fle causes female sterility and limits gene drive spread.

The paper investigates whether variation in multiplication rates of Plasmodium falciparum isolates under competitive conditions is determined by their intrinsic potential, finding a strong correlation with exponential growth rates.

The paper examines intrinsic multiplication rates of Plasmodium falciparum in Malaysian clinical isolates, finding no significant difference compared to African isolates, suggesting no adaptation to low transmission settings.

This study compares Plasmodium falciparum multiplication rates between hospital and community infections, finding higher rates in hospital isolates and a positive correlation with parasitaemia.