Bony De Kumar

This paper develops a non-viral genome-editing method called STEP-RNPs that effectively treats Angelman syndrome in mice and human neurons, showing functional genetic rescue without off-target effects.

This study identifies a T-cell intrinsic mechanism by which APOL1 risk alleles contribute to kidney rejection through altered calcium signaling and T-cell activation.

The paper investigates how HSF1 binding patterns remain consistent across different heat shock stimuli in cancer cells and links these patterns to transcription outcomes and chromatin accessibility changes.

The paper investigates how shared retinoic acid response elements regulate nascent transcription of Hoxb genes in mouse neural tube development using smFISH.

The paper identifies a novel DNA binding motif, HB1RE, associated with HOXB1-mediated gene repression in mouse ES cells.

This study investigates how a GATA3 mutation affects the transcriptional network involving ER, FOXA1, and GATA3, showing disrupted cooperation and altered chromatin localization.

The paper identifies combinatorial binding of Hoxa1 and TALE proteins on genome-wide targets and reveals their cross-regulatory interactions.