Nicholas E. Bambach

This study compares the effects of HrasG12V and KrasG12D mutations in thyroid cancer, showing HrasG12V induces follicular thyroid cancer with delayed MAPK activation and longer latency.

This study identifies KEAP1 mutations in thyroid cancer, showing they activate the NRF2 pathway, promote cell growth and migration, and reduce drug response.

The paper uses single-nuclei RNA sequencing to analyze pediatric thyroid cells, identifying seven major cell types and seven thyrocyte subclusters with distinct functions.