Functional analysis across model systems implicates ribosomal proteins in growth and proliferation defects associated with hypoplastic left heart syndrome
Tanja Nielsen, Anaïs Kervadec, Jeanne L. Theis, Maria Azzurra Missinato, James Marchant, Michaela R. Lynott, Katya Marchetti, Aashna Lamba, Xin-Xin I. Zeng, Marie Berenguer, Stanley M. Walls, Analyne Schroeder, Katja Birker, Greg Duester, Paul Grossfeld, , Alexandre R. Colas
The paper identifies ribosomal protein genes as contributors to hypoplastic left heart syndrome through functional analysis across multiple model systems.
eLife · Dec 11, 2025Peer-reviewedGenetic & Genomic Medicine