Author

Anagha J. Deshpande

Sanford Burnham Prebys Medical Discovery InstituteORCID 0000-0002-5653-2837Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

Aniruddha J. DeshpandeiD· 2 shared Aashna Lamba· 1 shared Adarsh RajeshiD· 1 shared Aditi Pedgaonkar· 1 shared Adrianna Abele· 1 shared Alexandre R. ColasiD· 1 shared Alice SoragniiD· 1 shared Angela M. Taravella OilliD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersGenomics

Aniruddha J. DeshpandeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Nucleosome stability safeguards cell identity, stress resilience and healthy aging

Hiroshi Tanaka, Brenna S. McCauley, Clara Guida, Xue Lei, Sha Li, Tatiana M. Moreno, K'leigh Guillotte, Zong Ming Chua, Adrianna Abele, Aashna Lamba, Rouven Arnold, Adarsh Rajesh, Marcos G. Teneche, Laurence Haddadin, Anagha J. Deshpande, , Peter D. Adams

The paper shows that reduced nucleosome stability impairs cell identity, stress resilience, and healthy aging across species.

bioRxiv · Sep 17, 2025 · PreprintGenomics

SUMO2 Inhibition Reverses Aberrant Epigenetic Rewiring Driven by Synovial Sarcoma Fusion Oncoproteins and Impairs Sarcomagenesis

Rema Iyer, Anagha J. Deshpande, Aditi Pedgaonkar, Pramod Akula Bala, Taehee Kim, Gerard L. Brien, Darren Finlay, Kristiina Vuori, Alice Soragni, Hiromi I Wetterstein, Rabi Murad, Aniruddha J. Deshpande

This study identifies SUMO2 as a selective vulnerability in synovial sarcoma, showing that SUMO2 inhibition reverses SS18-SSX-driven gene expression and impairs tumor growth.

The EMBO Journal · Aug 13, 2025Peer-reviewedCancer Biology

PopInf: An approach for reproducibly visualizing and assigning population affiliation in genomic samples of uncertain origin

Angela M. Taravella Oill, Anagha J. Deshpande, Heini M. Natri, Melissa A. Wilson

PopInf assigns genetic ancestry to samples with unknown origin using a reference panel, identifying discrepancies between reported race and inferred ancestry in TCGA liver cancer data.

Journal of Computational Biology · Oct 19, 2020Peer-reviewedGenomics