Author

Joseph Chen

Australian Regenerative Medicine InstituteORCID 0009-0002-3715-3871Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Guizhi Sun· 2 shared Jessica Anne NeiliD· 2 shared Jose Maria PoloiD· 2 shared Kanta SubbaraoiD· 2 shared Matthew J. GartneriD· 2 shared Randy SuryadinataiD· 2 shared Annette Fox· 1 shared Arada Hirankitti· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersMicrobiology

Guizhi Sun

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2 papers

Recent·Most cited

Viral replication and host response in airway epithelial cells predicts coronavirus pathogenicity and identifies HCoV-229E as an atypical seasonal coronavirus

Matthew J Gartner, Arada Hirankitti, Monika Mohenska, Stephany Sanchez, Guizhi Sun, Joseph Chen, Kevin Tang, Nikita Deshpande, Randy Suryadinata, Stephen Wilcox, Daniel P Rawlinson, Sarah L Londrigan, Daniel Steinfort, Philip Robinson, Jose Maria Polo, , Kanta Subbarao

This study compares viral replication and host responses in airway epithelial cells to distinguish pathogenic from seasonal coronaviruses, finding HCoV-229E induces severe epithelial injury despite limited replication.

bioRxiv · Nov 10, 2026 · PreprintMicrobiology

Contemporary seasonal human coronaviruses display differences in cellular tropism compared to laboratory-adapted reference strains

Matthew J. Gartner, Monique L Smith, Clyde Dapat, Yi Wen Liaw, Thomas Tran, Randy Suryadinata, Joseph Chen, Guizhi Sun, Rory A. Shepherd, George Taiaroa, Michael Roche, Wen Shi Lee, Philip J. Robinson, Jose Maria Polo, Kanta Subbarao, Jessica Anne Neil

This study isolates and characterizes contemporary seasonal human coronaviruses, showing differences in cell tropism and growth compared to lab-adapted strains.

Journal of Virology · Aug 27, 2025Peer-reviewedMicrobiology