Wen Shi Lee

This study examines immune dynamics in lymph nodes after YFV-17D vaccination, identifying robust B and T cell responses and a conserved germinal center program across different vaccines.

This study shows that vaccine strain selection and prior immunity influence antibody breadth against avian H5 hemagglutinin in mice.

A chimeric coronavirus spike vaccine combining SARS-CoV-2 RBD and HKU-1 scaffold domains elicits potent neutralising antibodies and CD4 T cell help in mice and macaques.

This study isolates and characterizes contemporary seasonal human coronaviruses, showing differences in cell tropism and growth compared to lab-adapted strains.

This study compares traditional mAb infusion with mRNA/LNP-based de novo mAb expression in mice, finding high serum concentrations but compromised protective capacity due to anti-drug antibodies.