Randy Suryadinata

Viral replication and host response in airway epithelial cells predicts coronavirus pathogenicity and identifies HCoV-229E as an atypical seasonal coronavirus

This study compares viral replication and host responses in airway epithelial cells to distinguish pathogenic from seasonal coronaviruses, finding HCoV-229E induces severe epithelial injury despite limited replication.

Epistasis facilitates the long-term antigenic evolution of the influenza B virus hemagglutinin

The paper analyzes the antigenic evolution of influenza B virus hemagglutinin over 8 decades, identifying epistatic networks that balance antigenic novelty with viral fitness.

Contemporary seasonal human coronaviruses display differences in cellular tropism compared to laboratory-adapted reference strains

This study isolates and characterizes contemporary seasonal human coronaviruses, showing differences in cell tropism and growth compared to lab-adapted strains.