Persia Akbari Omgba

The paper identifies mTOR's role in regulating developmental gene promoters in pluripotent mouse embryonic stem cells through interaction with PRC1 and RNA Polymerase II pausing.

This paper develops a hypoxia-mediated mouse embryo model to study neural patterning and shows hypoxia enhances anterior neural cell identity through HIF1a and TGFβ modulation.

CENTRE predicts cell-type-specific enhancer-target interactions using gene expression and ChIP-seq data, outperforming methods requiring extensive experimental data.