Cell BiologybioRxivPreprint
A fluorescent folding reporter uncovers myosin misfolding as a driver of Hypertrophic Cardiomyopathy
Renato Arnese, Philipp J. Dexheimer, Beatriz Escobar-Doncel…·Tim Clausen
This study identifies myosin misfolding as a driver of HCM using a fluorescent reporter and C. elegans model, showing dietary restrictions can reverse defects via autophagy.
DOI 10.1101/2025.02.10.636595