Author

James H. Hickling

Memorial Sloan Kettering Cancer CenterORCID 0009-0002-6677-2161Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:Hi-C· 1

Frequent Co-Authors

Abraham ShimiD· 1 shared Alex KentsisiD· 1 shared Arnold OuiD· 1 shared Ashley NicholsiD· 1 shared Conor WhelaniD· 1 shared Eléonore ToufektchaniD· 1 shared Ellie B Campbell· 1 shared Giulio FormentiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMolecular Biology

Abraham ShimORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

CAD-C: An engineered nuclease enables repair-free in situ proximity ligation and nucleosome-resolution chromosome walks in human cells

Jan Soroczynski, Lauren Anderson Westcott, Wu Zuo, Arnold Ou, Hera Canaj, James H. Hickling, Joanna Lan-Hing Yeung, Hideaki Konishi, Ellie B Campbell, Conor Whelan, Jennifer Balacco, Giulio Formenti, Viviana I. Risca

This paper introduces CAD-C, a new chromatin conformation capture method that improves resolution and efficiency over existing techniques like Micro-C and Hi-C.

bioRxiv · Jul 10, 2026 · PreprintGenomics

ER-tethering directs TREX1 penetration of a BAF-dependent barrier at micronuclei

Yanyang Chen, R. M. Norman, Eléonore Toufektchan, Xiaohan Luan, Abraham Shim, Hannah Rosenberg, Marton Tibor Kovacs, Ashley Nichols, James H. Hickling, Paolo Cifani, Alex Kentsis, Wen Zhou, John Maciejowski

The paper identifies BAF as a barrier that restricts TREX1 access to micronuclei, explaining the need for ER-tethering to enable TREX1 entry and suppress cGAS activation.

Molecular Cell · Mar 1, 2026Peer-reviewedMolecular Biology