Author

Rosa García

University of British ColumbiaORCID 0009-0002-7522-6920Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Megan K. LevingsiD· 2 shared Brian L. BressleriD· 1 shared Bruce Andrew VallanceiD· 1 shared Daniel YokosawaiD· 1 shared Dominic A. BoardmaniD· 1 shared Gabrielle BoucheriD· 1 shared Ho Pan ShamiD· 1 shared J. Ernesto Fajardo-Despaigne· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Megan K. LevingsORCID

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2 papers

Recent·Most cited

Reproducible detection of antigen-specific T cells and Tregs via standardized and automated activation-induced marker assay workflows

Torin Halvorson, Gabrielle Boucher, Daniel Yokosawa, Jinqing Huang, Rosa García, Lieke Sanderink, Lan Chen, Lorraine Liu, J. Ernesto Fajardo-Despaigne, Jasper Halvorson, Ryan R. Brinkman, Suzanne Vercauteren, Sylvie Lesage, Jonathan L. Bramson, John David Rioux, , Megan K. Levings

This study improves the reproducibility of antigen-specific T cell detection using standardized AIM assay workflows and automated analysis tools.

Cell Reports Methods · May 19, 2026Peer-reviewedImmunology

TYK2 inhibition enhances Treg differentiation and function while preventing Th1 and Th17 differnetiation

Karoliina Tuomela, Rosa García, Dominic A. Boardman, Pedram Tavakoli, Maria Ancheta-Schmit, Ho Pan Sham, Lihong Cheng, Mary D. Struthers, Brian L. Bressler, Bruce Andrew Vallance, Qihong Zhao, Megan K. Levings

This study shows that TYK2 inhibition promotes Treg differentiation and function while inhibiting Th1 and Th17 differentiation, suggesting its potential for tolerance induction.

Cell Reports Medicine · Aug 19, 2025Peer-reviewedImmunology