Maria Rodríguez‐López

The paper compares gene function and expression in dormant cells of yeast spores and killifish diapause embryos, finding conserved transcriptomic and proteomic changes across species.

The paper identifies microglial activation and alpha-synuclein oligomers as drivers of early neuroinflammation in Parkinson's disease using transcriptomic and aggregate profiling in early-stage brain samples.

The paper shows that DNA binding is essential for most functions of CSL proteins in fission yeast, including cell cycle, lipid metabolism, and genome integrity.

The paper uses phenomics and machine learning to predict protein functions in fission yeast, identifying novel roles and validating predictions through experimental validation.

The paper identifies a central state transition in yeast molecular networks linked to PKA and TOR signaling, showing how genetic variants can cause global or local molecular changes affecting multiple cellular traits.

The paper functionally profiles long intergenic non-coding RNAs (lincRNAs) in fission yeast by analyzing mutant phenotypes across various conditions.

The paper identifies age-related genome rearrangements in non-dividing fission yeast cells, linking them to R-loops and regulatory changes, and finds similar patterns in human brain cells.

This study introduces improved methods for studying chronological lifespan in fission yeast, identifying new ageing-associated genes with potential relevance to human ageing.

Pyphe automates and improves analysis of microbial fitness screens by processing colony size, viability, and growth curve data from low-cost imaging.

The paper identifies a natural variant in fission yeast Pyk1 that reduces glycolytic flux, increases respiration, and enhances oxidative-stress resistance but decreases growth.

The paper uses transposon mutagenesis and a hidden Markov model to identify functional elements in the fission yeast genome, finding that 90% of the genome has fitness consequences.

This study identifies ETS transcription factors as conserved regulators of longevity across species, showing their roles in modulating lifespan through gene expression programs.

The paper identifies 5775 novel lncRNAs in fission yeast and characterizes their regulation by RNA-processing pathways.

The paper identifies natural genetic variants associated with longevity in fission yeast by analyzing segregant pools and genome sequencing during aging.