Author

T. Ming Chu

University College LondonORCID 0009-0003-3344-0336Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alexandra J. McCrawiD· 1 shared Alice Kosmider· 1 shared Alicia M. ChenowethiD· 1 shared Anthony CheungiD· 1 shared Cenk CelikiD· 1 shared Daniela IancuiD· 1 shared Dongjun GuoiD· 1 shared Eloise WithnelliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Alexandra J. McCrawORCID

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2 papers

Recent·Most cited

ImmunologymAbsPeer-reviewedJul 13, 2025

Tuning antibody stability and function by rational designs of framework mutations

Joseph Chi-Fung Ng, Alicia M. Chenoweth, Maria Laura De Sciscio…·Franca Fraternali

This study designs framework mutations in antibodies to improve stability and function using a computational-experimental approach, showing that FW modifications can affect immunological functions beyond binding affinity.

3 citations

protein structuredeep learning

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJan 8, 2025

Balancing tumour proliferation and sustained cell cycle arrest through proteostasis remodelling drives immune niche compartmentalisation in breast cancer

Cenk Celik, Eloise Withnell, Pan Shi…·Maria Secrier

The paper quantifies G0 arrest and proliferation in breast cancer using single-cell and spatial data, identifying a prolonged G0 state and its spatial organization within an immunosuppressive niche.

4 citations

humanscRNA-seq

𝕏 PostBluesky