Author

Mathilda M. Willoughby

Georgia Institute of TechnologyORCID 0009-0003-4914-8452Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Approach:wet-lab / biochemical assay· 1 Organism:yeast· 1

Frequent Co-Authors

Alexander S. BrandisiD· 1 shared Amit R. ReddiiD· 1 shared Angela BoshnakovskaiD· 1 shared Ankit ShroffiD· 1 shared Bettina Homberg· 1 shared Bridget E. CrossmaniD· 1 shared Doron RapaportiD· 1 shared Felix JonasiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

Alexander S. BrandisORCID

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2 papers

Recent·Most cited

BiochemistryMolecular Biology of the CellPeer-reviewedJun 11, 2026

The ESCRT-0 protein HRS regulates hepatocellular lipid droplet catabolism

Mathilda M. Willoughby, Ankit Shroff, Bridget E. Crossman, Micah B. Schott

This paper identifies HRS as a regulator of lipid droplet catabolism in hepatocytes, showing it affects LD-lysosomal targeting and lysosomal function.

DOI 10.1091/mbc.e25-11-0536

humanproteomics

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Cell BiologybioRxivPreprintMay 9, 2024

The molecular mechanism of on-demand sterol biosynthesis at organelle contact sites

Naama Zung, Nitya Aravindan, Angela Boshnakovska…·Maya Schuldiner

This study identifies Yet3 as a protein that recruits sterol biosynthesis enzymes to ER contact sites, enabling on-demand sterol production and influencing organellar structure and function.

3 citations

yeastproteomics

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