Natalie Porat‐Shliom

This study shows that reducing Flotillin-2 increases T-DM1 internalization and cytotoxicity in HER2-amplified cancers by enhancing HER2 ubiquitination and internalization.

Imaging of mitochondria and lipid droplets (LDs) across mouse liver lobules shows fasting, not Western diet, expands mitochondria-LD contacts; PLIN5 phosphomutants tune contacts and lipid storage.

This study uses single-cell spatial proteomics to map human liver zonation patterns and shows their disruption in fibrosis.

This study identifies sex differences in tubuloglomerular feedback dynamics in rodent kidneys, showing males have higher oscillation frequencies but are more prone to TGF loss, leading to increased injury risk.