Uridine Phosphorylase-1 supports metastasis of mammary cancer by altering immune and extracellular matrix landscapes of the lung
Declan Whyte, Sophie L Fisher, Christopher G J McKenzie…·Cassie J. Clarke
Author
Cancer Research UK Scotland InstituteORCID 0009-0004-3173-5074Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Declan Whyte, Sophie L Fisher, Christopher G J McKenzie…·Cassie J. Clarke
Michalis Gounis, America V. Campos, Engy Shokry…·Cassie J. Clarke
The paper shows that breast cancer micrometastases alter metabolism to change extracellular vesicle production, creating an invasive microenvironment.
Jade A. Phillips, Jessica Perochon, Cai T. Johnson…·Julia B. Cordero
This study identifies biomechanical compartmentalization in the regenerating intestine and shows vascular Piezo1 influences angiogenesis and stem cell proliferation across species.
Luis Pardo, Madeleine Moore, Ruhi S. Deshmukh…·Jim C. Norman
This study shows that increased mRNA translation delays lung adenocarcinoma initiation and creates a vulnerability to MEK inhibitors in KRAS-driven tumors.
June Munro, Sarah L. Gillen, Louise E. Mitchell…·Martin Bushell
The paper optimizes sample preparation from primary mouse tissue to maintain RNA integrity for translatome analysis techniques like polysome and ribosome profiling.