Biomechanical Compartmentalisation Influences Angiogenesis and Stem Cell Proliferation in the Regenerating Intestine via Vascular Piezo.
Jade A. Phillips, Jessica Perochon, Cai T. Johnson, Matthew Walker, Colin Nixon, Mark M. Hughes, André Barros-Carvalho, Yachuan Yu, Louise E. Mitchell, Karen Blyth, Massimo Vassalli, Julia B. Cordero
This study identifies biomechanical compartmentalization in the regenerating intestine and shows vascular Piezo1 influences angiogenesis and stem cell proliferation across species.
bioRxiv · Apr 16, 2025 · PreprintDevelopmental Biology