Author

Leke Bytyqi

University of Kentucky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam D. BachstetteriD· 2 shared Kelly N. Roberts· 2 shared MaKayla F. CoxiD· 2 shared Teresa Macheda· 2 shared Bruce F. O’HaraiD· 1 shared Carrie E. Johnson· 1 shared Elika Z. MoallemiD· 1 shared Emma K. Higgins· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Adam D. BachstetterORCID

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2 papers

Recent·Most cited

Closed-head injury produces a delayed, region-specific defect in glucose-carbon routing at the pyruvate branchpoint in APP/PS1 KI mice

Elika Z. Moallem, Ronald C. Bruntz, MaKayla F. Cox, Leke Bytyqi, Taylor K Roberts, Samir P. Patel, Teresa Macheda, Kelly N. Roberts, Emma K. Higgins, Ramon C. Sun, Matthew S. Gentry, Patrick G. Sullivan, Lance A. Johnson, Adam D. Bachstetter

The paper investigates delayed glucose metabolism changes in APP/PS1 KI mice after closed-head injury, finding increased pyruvate and lactate labeling in cortex and hippocampus 8 months post-injury.

bioRxiv · Oct 6, 2026 · PreprintNeuroscience

Dim light at night impacts circadian rhythms and Alzheimer's disease-like neuroinflammation and neuropathology in humanized APP SAA knock-in mice

Marilyn J. Duncan, Margaret R. Hawkins, Leke Bytyqi, Haleigh R Whitlock, Savannah M Shepard, MaKayla F. Cox, Esther G. Drinkard, Teresa Macheda, Kelly N. Roberts, Katharina Köhler, Mariella Schmidt, Carrie E. Johnson, Sridhar Sunderam, Bruce F. O’Hara, Michael Paul Murphy, Adam D. Bachstetter

This study shows that dim light at night disrupts circadian rhythms and increases amyloid pathology and microglial activation in a mouse model of Alzheimer's disease.

SLEEP · Feb 20, 2026Peer-reviewedNeuroscience