Jiajia Wang

This study develops tetrasulfide-incorporated mesoporous silica nanoparticles to enhance mRNA delivery by optimizing morphology and chemistry, showing improved cellular uptake and mRNA stability.

This study shows that biomimetic virus-like mesoporous silica nanoparticles activate NK cells through monocyte crosstalk by optimizing spike length, surface functionalization, and cell membrane coating.

This study shows virus-like nanospikes activate Piezo1 to enhance STING signaling in macrophages, promoting M1 polarization through mechanical and inflammatory signals.

This paper designs tunable, rigid spike architectures on virus-like porous silica nanoparticles to enhance antigen delivery and immune response, showing improved vaccine efficacy compared to traditional adjuvants.

This study investigates how spike structures on virus-like nanoparticles enhance immune responses in macrophages through proteomic analysis of signaling pathways.