Jussi Hepojoki

This study examines histopathological and viral protein expression features of Boid Inclusion Body Disease in boa constrictors, finding higher IB and NP scores in recent cases and no significant link between NP scores and inflammation.

This study develops tetrasulfide-incorporated mesoporous silica nanoparticles to enhance mRNA delivery by optimizing morphology and chemistry, showing improved cellular uptake and mRNA stability.

This study designs and validates protease-resistant antiviral peptides that inhibit SARS-CoV-2 fusion, showing improved efficacy in vitro and in vivo.

This study develops hybrid lipid-VLPSi nanoparticles to enhance mRNA delivery, finding that amino-modified VLPSi significantly improves transfection efficiency compared to conventional LNPs.

This study investigates the protein expression of Swiss snake colony virus 1 (SwSCV-1) and finds it encodes only a single form of the delta antigen, unlike hepatitis D virus (HDV), and the additional ORF2 does not produce a functional protein.

This study shows deltaviruses use helper virus particles as Trojan Horses for cell entry, revealing a new mode of viral transmission.

This study investigates how spike structures on virus-like nanoparticles enhance immune responses in macrophages through proteomic analysis of signaling pathways.

The paper examines the morphology of haemolymphatic tissues in healthy and Boid Inclusion Body Disease (BIBD)-affected boa constrictors, identifying structural features and disease-related changes.

The paper reports on neoplastic vascular proliferations in rainbow boas with boid inclusion body disease, linking reptarenavirus infection to potential neoplastic processes.

The paper examines circulating mucosal-like IgA responses in Puumala orthohantavirus infection and finds they correlate with AKI severity and pro-inflammatory effects.

The paper introduces a 1.2x genome infectious clone strategy for deltaviruses, demonstrating its ability to initiate replication in snake cells without helper viruses.