Author

Davide C. Recchia

Utrecht UniversityORCID 0009-0004-5791-074XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Tuncay BaubeciD· 4 shared Richard Cardoso da SilvaiD· 3 shared Nina SchmolkaiD· 2 shared Angela TopiciD· 1 shared Christina AmbrosiiD· 1 shared Ino D. KaremakeriD· 1 shared Jahnavi BhaskaraniD· 1 shared Kelly E. SteckeriD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersMolecular Biology

Tuncay BaubecORCID

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4 papers

Recent·Most cited

A modular toolbox for in cellulo screening of small molecule inhibitors targeting chromatin reader domains

Davide C. Recchia, Richard Cardoso da Silva, Niklas Kupfer, Angela Topic, Sara Giuliani, Rodrigo Villaseñor, Tuncay Baubec

The paper develops a modular cell line platform with synthetic chromatin reader constructs to assess small molecule inhibitors targeting bromodomains in living cells.

bioRxiv · Sep 6, 2025 · PreprintMolecular Biology

Probing DNA damage sites reveals context-dependent and novel DNA damage response factors

Richard Cardoso da Silva, Davide C. Recchia, Vincent Portegijs, María Cristina Trueba Sánchez, Kelly E. Stecker, Sander van den Heuvel, Tuncay Baubec

This study uses engineered protein probes to track DNA damage dynamics and identify novel DNA damage response factors in living cells and animals.

bioRxiv · Oct 23, 2024 · PreprintMolecular Biology

SETD2 promotes PAF1C interactions with the elongating RNA Pol II and is required for neuronal differentiation

Christina Ambrosi, Ramon Pfaendler, Stefan Butz, Davide C. Recchia, Xue Bao, Nina Schmolka, Tuncay Baubec

The paper identifies SETD2's role in neuronal differentiation by promoting PAF1C interactions with RNA Pol II and shows its requirement for neuronal gene expression during late differentiation stages.

bioRxiv · Oct 23, 2024 · PreprintMolecular Biology

Dissecting the roles of MBD2 isoforms in regulating NuRD complex function during cellular differentiation

Nina Schmolka, Ino D. Karemaker, Richard Cardoso da Silva, Davide C. Recchia, Vincent Spegg, Jahnavi Bhaskaran, Michael Teske, Nathalie P. Vroegindeweij-de Wagenaar, Matthias Altmeyer, Tuncay Baubec

This study investigates the roles of MBD2 and MBD3 isoforms in NuRD complex function during differentiation, showing that MBD2b can fully rescue MBD3 loss while MBD2t cannot.

Nature Communications · Jun 29, 2023Peer-reviewedMolecular Biology