Author

Robert M. Fulbright

Cornell UniversityORCID 0009-0004-6323-6472Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Assay:DNA methylation· 2 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Chuang TaniD· 2 shared James M. BergeriD· 2 shared James T. InmaniD· 2 shared Joshua JeongiD· 2 shared Michelle Dong WangiD· 2 shared Curtis BeckiD· 1 shared Deanna GotteiD· 1 shared Glenn HaukiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersBiophysics

Chuang TanORCID

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Author profile →

3 papers

Recent·Most cited

Chromatin Buffers Torsional Stress During Transcription

Jin Qian, Lucyna Lubkowska, Shuming Zhang, Chuang Tan, Yifeng Hong, Xiaomeng Jia, Robert M. Fulbright, James T. Inman, Taryn M. Kay, Joshua Jeong, Glenn Hauk, Deanna Gotte, James M. Berger, Mikhail Kashlev, Michelle Dong Wang

This study shows that chromatin buffers torsional stress during transcription by enabling Pol II to transcribe through nucleosomes more efficiently than on single-nucleosome substrates.

Science · Dec 18, 2025Peer-reviewedBiophysics

Human Topoisomerase IIα Promotes Chromatin Condensation Via a Phase Transition

Meiling Wu, Curtis Beck, Joyce H. Lee, Robert M. Fulbright, Joshua Jeong, James T. Inman, Mitchell V Woodhouse, James M. Berger, Michelle Dong Wang

This study identifies a new role for human topoisomerase IIα in promoting chromatin condensation through a polymer-collapse phase transition, independent of its catalytic activity.

bioRxiv · Oct 15, 2024 · PreprintBiophysics

Transcription Factor Regulation of RNA polymerase’s Torsional Capacity

Jie Ma, Chuang Tan, Xiang Gao, Robert M. Fulbright, Jeffrey W. Roberts, Michelle D. Wang

This study shows that the transcription factor GreB enhances RNA polymerase's torsional capacity by reducing backtracking and increasing torque generation by 65%.

bioRxiv · Apr 23, 2018 · PreprintBiophysics