Author

Melisa Isado

Columbia UniversityORCID 0009-0004-7797-0352Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Chanju JungiD· 1 shared Diego MariniD· 1 shared Dieter M. EgliiD· 1 shared Gue‐Ho HwangiD· 1 shared Hong-Su Jang· 1 shared Jae‐Sung WooiD· 1 shared Jia L. XuiD· 1 shared Jimin Kim· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Chanju JungORCID

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1 paper

Recent·Most cited

Efficient base editing and development in human embryos without chromosomal alterations

Stepan Jerabek, Jimin Kim, Julie Sung, Chanju Jung, Marcos Iuri Roos Kulmann, Melisa Isado, Hong-Su Jang, Meng Li, Sakshi Bhatele, Michelle D. Kappy, Shuangyi Xu, Gue‐Ho Hwang, Jia L. Xu, Diego Marin, Jae‐Sung Woo, , Dieter M. Egli

This study shows that base editing in human embryos produces efficient on-target changes without chromosomal abnormalities or large deletions, unlike CRISPR/Cas9-induced DSBs.

bioRxiv · Jun 1, 2026 · PreprintGenetics