Author

Sakshi Bhatele

Columbia UniversityORCID 0000-0002-2514-193XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Dieter M. EgliiD· 2 shared Amnon KoreniD· 1 shared Chanju JungiD· 1 shared Dashiell J. MasseyiD· 1 shared Diego MariniD· 1 shared Gue‐Ho HwangiD· 1 shared Hong-Su Jang· 1 shared Jae‐Sung WooiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersGenetics

Dieter M. EgliORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintJun 1, 2026

Efficient base editing and development in human embryos without chromosomal alterations

Stepan Jerabek, Jimin Kim, Julie Sung…·Dieter M. Egli

This study shows that base editing in human embryos produces efficient on-target changes without chromosomal abnormalities or large deletions, unlike CRISPR/Cas9-induced DSBs.

12 citations

humanexperimental assay

𝕏 PostBluesky

GeneticsCell ReportsPeer-reviewedJan 1, 2024

Incomplete Reprogramming of DNA Replication Timing in Induced Pluripotent Stem Cells

Matthew M. Edwards, Ning Wang, Dashiell J. Massey…·Amnon Koren

The paper examines DNA replication timing in iPSCs, finding that some exhibit delayed replication at heterochromatic regions, which persists through differentiation and may affect their quality.

12 citations

mouseDNA methylation

𝕏 PostBluesky