Author

Ntombizodwa Makuyana

Babraham InstituteORCID 0009-0004-8275-1162Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein design· 1 Assay:protein structure· 1

Frequent Co-Authors

A. J. DashwoodiD· 1 shared Adrian ListoniD· 1 shared Alvaro R. HernandeziD· 1 shared Arman GhodsiniaiD· 1 shared Bidesh MahataiD· 1 shared Clara Veiga-VillauriziD· 1 shared Daniel HebenstreitiD· 1 shared Esam KhanfariD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. J. DashwoodORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 29, 2025

Immune cell de novo steroidogenesis regulates inflammation resolution and recovery in acute lung injury

Hosni A. M. Hussein, Sanu Korumadathil Shaji, Clara Veiga-Villauriz…·Bidesh Mahata

This study shows that immune cell steroidogenesis is essential for resolving inflammation and promoting recovery in acute lung injury.

DOI 10.1101/2025.08.29.673039

mouseexperimental assay

𝕏 PostBluesky

ImmunologyComputational and Structural Biotechnology JournalPeer-reviewedJan 1, 2025

Directed disruption of IL2 aggregation sites produces designer biologics with enhanced specificity coupled to improved production capacity

A. J. Dashwood, Ntombizodwa Makuyana, Rob van der Kant…·Adrian Liston

This paper designs IL2 muteins with enhanced Treg or CD8 T cell specificity and improved production by predicting mutations using SolubiS and testing their functional and structural properties.

3 citations

𝕏 PostBluesky