Author

Paule E. H. M’Bra

Université de SherbrookeORCID 0009-0005-0013-5241Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1

Frequent Co-Authors

Anne Aumont· 3 shared Karl J. L. FernandesiD· 3 shared Laura K. HamiltoniD· 2 shared Manon GaloppiniD· 2 shared Marian Mayhue· 2 shared Sophia Mailloux· 2 shared Anne Castonguay· 1 shared Annick Vachon· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Anne Aumont

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NeurosciencebioRxivPreprintFeb 25, 2025

Ketogenic interventions prevent alterations of the gut microbiome in transgenic Alzheimer Disease mice

Paule E. H. M’Bra, Mariano Avino, Evelyne Ng Kwan Lim…·Karl J. L. Fernandes

This study shows ketogenic diets restore gut microbiome alterations in Alzheimer's mice by reducing Bifidobacterium and increasing short-chain fatty acid-producing bacteria.

DOI 10.1101/2025.02.25.640129

mousemetagenomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintSep 4, 2024

Ketogenic interventions restore cognition and modulate peripheral metabolic dysfunctions in Alzheimer's disease mouse models

Paule E. H. M’Bra, Laura K. Hamilton, Gaël Moquin‐Beaudry…·Karl J. L. Fernandes

This study shows that two ketogenic diets improve cognition and metabolic health in Alzheimer's disease mouse models, with distinct effects on peripheral metabolism.

DOI 10.1101/2024.09.04.610637

mousemetabolomics

𝕏 PostBluesky

NeuroscienceScientific ReportsPeer-reviewedApr 2, 2024

Central inhibition of Stearoyl-CoA Desaturase has minimal effects on the peripheral metabolic symptoms of the 3xTg Alzheimer's disease mouse model

Laura K. Hamilton, Paule E. H. M’Bra, Sophia Mailloux…·Karl J. L. Fernandes

This study shows that inhibiting Stearoyl-CoA Desaturase in the brain of 3xTg-AD mice improves cognitive function without affecting peripheral metabolic symptoms.

5 citations

mouseexperimental assay

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