Author

Marian Mayhue

Université de Sherbrooke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1

Frequent Co-Authors

Anne Aumont· 3 shared Karl J. L. FernandesiD· 3 shared Annick Vachon· 2 shared Marta TurriiD· 2 shared Mélanie PlourdeiD· 2 shared Myriam Aubin· 2 shared Paule E. H. M’BraiD· 2 shared Anne Castonguay· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Anne Aumont

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

In vivo inhibition of stearoyl-CoA desaturase modulates the hippocampal fatty acid profile and restores density of dendritic spines in the aggressive 5xFAD model of Alzheimer s disease

Marta Turri, Myriam Aubin, Anne Aumont, Annick Vachon, Jessica Avila Lopez, Marian Mayhue, Mélanie Plourde, Karl J. L. Fernandes

This study shows that inhibiting SCD improves fatty acid profiles and restores dendritic spine density in a 5xFAD Alzheimer's model.

bioRxiv · Aug 27, 2025 · PreprintNeuroscience

Ketogenic interventions prevent alterations of the gut microbiome in transgenic Alzheimer Disease mice

Paule E. H. M’Bra, Mariano Avino, Evelyne Ng Kwan Lim, Marian Mayhue, Philippe Balthazar, Anne Aumont, Karine Prévost, Éric Massé, Karl J. L. Fernandes

This study shows ketogenic diets restore gut microbiome alterations in Alzheimer's mice by reducing Bifidobacterium and increasing short-chain fatty acid-producing bacteria.

bioRxiv · Feb 25, 2025 · PreprintNeuroscience

Ketogenic interventions restore cognition and modulate peripheral metabolic dysfunctions in Alzheimer's disease mouse models

Paule E. H. M’Bra, Laura K. Hamilton, Gaël Moquin‐Beaudry, Myriam Aubin, Chenicka Lyn Mangahas, Federico Pratesi, Elsa Brunet‐Ratnasingham, Anne Castonguay, Sophia Mailloux, Manon Galoppin, Megan Bernier, Marta Turri, Annick Vachon, Marian Mayhue, Anne Aumont, , Karl J. L. Fernandes

This study shows that two ketogenic diets improve cognition and metabolic health in Alzheimer's disease mouse models, with distinct effects on peripheral metabolism.

bioRxiv · Sep 4, 2024 · PreprintNeuroscience