Author

Hua Luo

University of TorontoORCID 0009-0005-0914-6086Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:multiome· 1

Frequent Co-Authors

Angelo KaraiskakisiD· 2 shared Craig A. SmibertiD· 2 shared Howard D. LipshitziD· 2 shared Timothy C.H. Low· 2 shared Aaron L. GoldmaniD· 1 shared Chalini Weerasooriya· 1 shared Elizabeth R. GavisiD· 1 shared Najeeb U. SiddiquiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersGenetics

Angelo KaraiskakisORCID

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2 papers

Recent·Most cited

GeneticsGeneticsPeer-reviewedNov 6, 2025

The ORB2 RNA-binding protein negatively regulates its target transcripts during the Drosophila maternal-to-zygotic transition via its functionally conserved Zinc binding 'ZZ' domain

Timothy C.H. Low, Hua Luo, Chalini Weerasooriya…·Howard D. Lipshitz

This study identifies ORB2 as a regulator of maternal mRNAs during the Drosophila MZT, showing its ZZ domain mediates repression through interactions with post-transcriptional regulators.

4 citations

Drosophilabulk RNA-seq

𝕏 PostBluesky

Developmental BiologyScience AdvancesPeer-reviewedApr 12, 2024

Smaug regulates germ plasm synthesis and primordial germ cell number in Drosophila embryos by repressing the oskar and bruno 1 mRNAs

Najeeb U. Siddiqui, Angelo Karaiskakis, Aaron L. Goldman…·Howard D. Lipshitz

The paper identifies Smaug's role in repressing osk and bru1 mRNAs to regulate germ plasm synthesis and PGC number in Drosophila embryos.

11 citations

Drosophilamultiome

𝕏 PostBluesky