Author

Lindy K. Brastrom

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:organoid / primary culture· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Charlie J. ChildsiD· 2 shared Jason R. SpenceiD· 2 shared Tristan FrumiD· 2 shared Alexis S. Fine· 1 shared Ansley S. ConcholaiD· 1 shared Claudia LoebeliD· 1 shared Darrell N. KottoniD· 1 shared Donia W AhmediD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Charlie J. ChildsORCID

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Author profile →

2 papers

Recent·Most cited

Nascent matrix deposition supports alveolar organoid formation from aggregates in synthetic hydrogels

Madeline K. Eiken, Charlie J. Childs, Lindy K. Brastrom, Tristan Frum, Eleanor M. Plaster, Donia W Ahmed, Ryan C. Spencer, Orren Shachaf, Suzanne Pfeiffer, Justin E. Levine, Konstantinos–Dionysios Alysandratos, Darrell N. Kotton, Jason R. Spence, Claudia Loebel

This study develops a Matrigel-free method using synthetic hydrogels to form alveolar organoids, showing they secrete their own extracellular matrix for growth.

Stem Cell Reports · Dec 12, 2024Peer-reviewedCell Biology

Stable iPSC-derived NKX2-1+ Lung Bud Tip Progenitor Organoids Give Rise to Airway and Alveolar Cell Types

Renee F. C. Hein, Ansley S. Conchola, Alexis S. Fine, Zhiwei Xiao, Tristan Frum, Lindy K. Brastrom, Mayowa A. Akinwale, Charlie J. Childs, Yu-Hwai Tsai, Emily M. Holloway, Sha Huang, John E. Mahoney, Idse Heemskerk, Jason R. Spence

This study develops iPSC-derived lung bud tip progenitor organoids that can be expanded and differentiated into airway or alveolar organoids, showing transcriptional similarity to in vivo progenitors.

Development · Aug 30, 2022Peer-reviewedDevelopmental Biology