Riccardo Bocchi

This study shows that post-mitotic cortical neurons retain birthdate-dependent differentiation potential, with early-born neurons maintaining a broader repertoire than late-born neurons.

The paper identifies distinct developmental origins of neocortical astrocytes using multimodal techniques and reveals their unique lineage and developmental trajectory.

This study compares prenatal cortical development in two rodents, showing that major developmental milestones occur prenatally in Acomys, challenging the view that postnatal experience is essential for early brain maturation.

This study shows that loss of Lhx2 increases astrocyte proliferation in upper cortical layers and induces reactive gliosis-like signatures without injury.

The paper identifies a shared inflammatory glial cell signature after brain injury using spatial and single-cell transcriptomics in mice, showing common injury-regulated genes across astrocytes, microglia, and oligodendrocyte precursor cells.

The paper identifies two distinct astrocyte lineages in the mouse neocortex using single-cell RNA sequencing and TrackerSeq, revealing their developmental origins and regulatory mechanisms.