BiophysicsbioRxivPreprint
Covalent Drug binding in Live Cells Monitored by Mid-IR Quantum Cascade Laser Spectroscopy: Photoactive Yellow Protein as a Model System
Srijit Mukherjee, Steven D.E. Fried, Nathalie Y. Hong…·Steven G. Boxer
This paper develops a mid-IR quantum cascade laser spectroscopy method to detect drug-target interactions in live cells using photoactive yellow protein as a model system.